Title of article
Secondary alcohols act as better nucleophiles than primary alcohols in the lipase-catalyzed regioselective deacylation of dihydroxybenzenes acylated at both phenolic hydroxyls
Author/Authors
Miyazawa، نويسنده , , Toshifumi and Hamada، نويسنده , , Manabu and Morimoto، نويسنده , , Ryohei and Murashima، نويسنده , , Takashi and Yamada، نويسنده , , Takashi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
8334
To page
8337
Abstract
Candida antarctica lipase B (CAL-B) was found to be highly regioselective as well as active in the deacylation of resorcinols and hydroquinones acylated at both phenolic hydroxyls. Contrary to expectation, secondary alcohols acted as better nucleophiles than primary alcohols in these enzymatic deacylations.
Keywords
Hydroquinones , Candida antarctica lipase B , regioselective deacylation , Resorcinols , Secondary alcohols
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1857324
Link To Document