Author/Authors :
Murashima، نويسنده , , Takashi and Hayata، نويسنده , , Kazuyuki and Saiki، نويسنده , , Yumi and Matsui، نويسنده , , Jun and Miyoshi، نويسنده , , Daisuke and Yamada، نويسنده , , Takashi and Miyazawa، نويسنده , , Toshifumi and Sugimoto، نويسنده , , Naoki، نويسنده ,
Abstract :
The DNAs modified with tetraphenyl porphyrin at the center of 13mer oligonucleotide were synthesized using phosphoramidite chemistry and automated DNA synthesis. When the porphyrin modified oligonucleotide was annealed with its complementary strand, they formed a standard B-form duplex. The porphyrin moiety intercalated in the duplex, and moderately lowered the thermal stability.
