Title of article
Asymmetric crystallization of bisguanidinobenzene derivatives
Author/Authors
Nakanishi، نويسنده , , Waka and Ogino، نويسنده , , Akiko and Kawahata، نويسنده , , Masatoshi and Yamaguchi، نويسنده , , Kentaro and Ishikawa، نويسنده , , Tsutomu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
8526
To page
8530
Abstract
We show that the mono-N-methylated and -ethylated derivatives of the achiral compound bisguanidinobenzene undergo spontaneous asymmetric crystallization into a chiral form with chiral space group P212121. The absolute configurations of the chiral crystals were determined by X-ray crystallography and correlated with circular dichroism (CD) spectra recorded in the solid state. The corresponding protonated and isopropylated derivatives, by contrast, afforded achiral crystals.
Keywords
CD , Guanidine , Asymmetric crystallization , X-ray diffraction
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1857400
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