Author/Authors :
Collot، نويسنده , , Mayeul and Garcia-Moreno، نويسنده , , Maria Isabel and Fajolles، نويسنده , , Christophe and Roux، نويسنده , , Michel and Mauclaire، نويسنده , , Laurent and Mallet، نويسنده , , Jean-Maurice، نويسنده ,
Abstract :
Methylated 6A,6D-diamino 6A,6D-dideoxy β-cyclodextrin 4 was coupled with three cholesterol substituted glutaric or succinic acids 5–7 to give amphiphilic cyclodextrins 1–3 with good yields. The succinic acid derivative 1, a typical member of this new family, has shown good compatibility with phosphatidyl choline monolayer and bilayer as confirmed by deuterium magnetic nuclear resonance (2H NMR).
Keywords :
Amphiphilic cyclodextrins , Deuterium NMR , cyclic anhydride , Langmuir monolayer