Title of article
The Vilsmeier reagent as an efficient acid activator for the synthesis of β-lactams
Author/Authors
Jarrahpour، نويسنده , , Aliasghar and Zarei، نويسنده , , Maaroof، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
8712
To page
8714
Abstract
The Vilsmeier reagent (chloromethylenedimethylammonium chloride) has been used as an efficient and cheap acid activator for the one-step Staudinger reaction of substituted acetic acids and imines under mild conditions. This reaction is clean and the by-products are DMF and triethylamine hydrochloride which were removed by simple aqueous work-up.
Keywords
Vilsmeier reagent , ?-Lactam , Staudinger reaction , acid activator , Cycloaddition reaction
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1857472
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