Author/Authors :
Tomita، نويسنده , , Yuichi and Ichikawa، نويسنده , , Yoshiyuki and Itoh، نويسنده , , Yoshimitsu and Kawada، نويسنده , , Kosuke and Mikami، نويسنده , , Koichi، نويسنده ,
Abstract :
Ketone zincate-type enolates can be applied to radical trifluoromethylation for the general synthesis of α-CF3-ketones, cyclopentanones in particular. The addition of diethylzinc to lithium enolates is the key in the preparation of the zincate-type enolates for efficient radical trifluoromethylation.
