Title of article
Synthesis of substituted 2-phenylhistamines via a microwave promoted Suzuki coupling
Author/Authors
Skoumbourdis، نويسنده , , Amanda P. and Moore، نويسنده , , Susanna and Landsman، نويسنده , , Marc and Thomas، نويسنده , , Craig J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
9140
To page
9143
Abstract
Substitutions on the 2-position of the imidazole ring of histamine have proven useful in a number of biochemical settings. Current art for the synthesis of these constructs relies upon a cumbersome and low-yielding condensation reaction. Here-in we report a new procedure for the synthesis of a series of substituted 2-phenylhistamines utilizing a microwave-promoted Suzuki coupling.
Keywords
2-Phenylhistamine , Heteroaromatic Suzuki coupling , Microwave promoted Suzuki coupling
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1857604
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