Title of article
Opening of azetidinium ions with C-nucleophiles
Author/Authors
Couty، نويسنده , , François and David، نويسنده , , Olivier and Drouillat، نويسنده , , Bruno، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
9180
To page
9184
Abstract
The nucleophilic opening of functionalized azetidinium ions by C-nucleophiles was screened. Malonate and cyanide anions reacted in a highly regio- and chemoselective way leading to functionalized pure amines. The success of this reaction was found to be highly dependent on the basicity of the involved nucleophiles and the competitive reactions induced by too basic reagents were identified.
Keywords
azetidinium ions , strain , azetidines
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1857614
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