Author/Authors :
Zambon، نويسنده , , Alfonso and Borsato، نويسنده , , Giuseppe and Brussolo، نويسنده , , Stefania and Frascella، نويسنده , , Pietrogiulio and Lucchini، نويسنده , , Vittorio، نويسنده ,
Abstract :
A novel rearrangement process involving the migration of trimethylstannanyl or trimethylsilanyl groups around the thiazole ring provides access to either 2- or 5-metallated thiazoles by tuning the reaction conditions. The proposed mechanism, based on experimental evidence, is characterized by the catalytic role of thiazole bisadducts as metal-transfer agents.
