Author/Authors :
Briand، نويسنده , , Benoît and Kotzur، نويسنده , , Nico and Hagen، نويسنده , , Michael، نويسنده ,
Abstract :
Native chemical ligation (NCL) at Glu–Cys sites requires carboxyl protection that is compatible with the chemistry used for assembling the peptides. In the case of Fmoc-chemistry our novel BCMACM-group is particularly suitable for NCL because of the good solubility in aqueous solvent systems and mild conditions of photolytic removal.
