Title of article :
A simple procedure for the esterification of alcohols with sodium carboxylate salts using 1-tosylimidazole (TsIm)
Author/Authors :
Soltani Rad، نويسنده , , Mohammad Navid and Behrouz، نويسنده , , Somayeh and Faghihi، نويسنده , , Mohammad Ali and Khalafi-Nezhad، نويسنده , , Ali، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
An efficient and selective method for esterification of alcohols using N-(p-toluenesulfonyl)imidazole (TsIm) is described. In this method, alcohols are refluxed with a mixture of RCO2Na (R: alkyl and aryl), TsIm, and triethylamine in the presence of catalytic amounts of tetra-n-butylammonium iodide (TBAI) in DMF to afford the corresponding esters in good yields. This methodology is highly efficient for various structurally diverse alcohols with selectivity for ROH: 1° > 2° > 3°.
Keywords :
Esterification , alcohol , Carboxylic salts , Tetrabutylammonium iodide (TBAI) , N-(p-Toluenesulfonyl)imidazole (TsIm) , Triethylamine (TEA)
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
