• Title of article

    Synthesis of potent BCRP inhibitor—Ko143

  • Author/Authors

    Li، نويسنده , , Yuexian and Hayman، نويسنده , , Erik and Plesescu، نويسنده , , Mihaela and Prakash، نويسنده , , Shimoga R.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    4
  • From page
    1480
  • To page
    1483
  • Abstract
    Two routes for the synthesis of potent BCRP inhibitor—Ko143 are reported. The key intermediate, 6-methoxytryptophan derivative, was synthesized by an improved procedure, ytterbium triflate-promoted coupling between 6-methoxyindole and optically active 1-benzyl-2-methyl-(S)-1,2-aziridinecarboxylate in the second protocol.
  • Keywords
    BCRP inhibitor , ytterbium triflate , Aziridinecarboxylate , Ko143
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2008
  • Journal title
    Tetrahedron Letters
  • Record number

    1858363

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1858363