Author/Authors :
Kiyooka، نويسنده , , Syun-ichi and Matsumoto، نويسنده , , Satoshi and Kojima، نويسنده , , Masafumi and Sakonaka، نويسنده , , Kazuyuki and Maeda، نويسنده , , Hirofumi، نويسنده ,
Abstract :
[((R)-BINAP)Pt(μ-OH)]2·2OTf catalyzed the enantioselective aldol reaction of aldehydes with 1-methoxy-2-methyl-(1-trimethylsilyloxy)propene at room temperature in dry DMF in high yields with enantioselectivity up to 92%. This is a versatile example of the catalytic enantioselective aldol reaction using a silyl ketene acetal promoted by (μ-hydroxo)-platinum complexes under mild conditions.
