Title of article
(μ-Hydroxo)-platinum complex-catalyzed enantioselective aldol reaction of aldehydes with 1-methoxy-2-methyl-1-(trimethylsilyloxy)propene in DMF
Author/Authors
Kiyooka، نويسنده , , Syun-ichi and Matsumoto، نويسنده , , Satoshi and Kojima، نويسنده , , Masafumi and Sakonaka، نويسنده , , Kazuyuki and Maeda، نويسنده , , Hirofumi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
1589
To page
1592
Abstract
[((R)-BINAP)Pt(μ-OH)]2·2OTf catalyzed the enantioselective aldol reaction of aldehydes with 1-methoxy-2-methyl-(1-trimethylsilyloxy)propene at room temperature in dry DMF in high yields with enantioselectivity up to 92%. This is a versatile example of the catalytic enantioselective aldol reaction using a silyl ketene acetal promoted by (μ-hydroxo)-platinum complexes under mild conditions.
Keywords
Enantioselective aldol reaction , (?-Hydroxo)-platinum complex
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1858421
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