Title of article :
A novel synthesis of γ-lactones by tandem epoxide opening-cyclization reaction mediated by samarium(II) diiodide
Author/Authors :
Park، نويسنده , , Heui Sul and Kwon، نويسنده , , Doo Won and Lee، نويسنده , , Kieseung and Kim، نويسنده , , Yong Hae، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
Various epoxy esters readily reacted with SmI2 (2 equiv) in the presence of ethyl bromoacetate (1 equiv) and HMPA (6 equiv) under mild conditions (THF, −78 °C, 2 h, Ar) providing the corresponding γ-lactones via tandem epoxide opening-cyclization reaction in good to excellent yields.
Keywords :
?-Lactone , ?-Butyrolactone , Tandem reaction , Samarium diiodide
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
