Author/Authors :
van Zutphen، نويسنده , , Steven and Mora، نويسنده , , Guilhem and Margarit، نويسنده , , Vicente J. and Le Goff، نويسنده , , Xavier F. and Carmichael، نويسنده , , Duncan and Le Floch، نويسنده , , Pascal، نويسنده ,
Abstract :
Using a one-pot four-step reaction a readily available phospholide was converted efficiently to a 2-carboxyphosphole. This compound can be used as a building block for the synthesis of phosphole-containing peptides, where the phosphole can serve as a coordination site for late transition metals and may affect the secondary structure of the peptide.
Keywords :
P Ligands , sigmatropic rearrangement , Microwave-assisted synthesis , Phosphorus heterocycles
