Title of article
Hydroarylation of bicyclic, unsaturated dicarboximides: access to aryl-substituted, bridged perhydroisoindoles
Author/Authors
Gِksu، نويسنده , , Gِkce and Gül، نويسنده , , Melek and ضcal، نويسنده , , Nüket and Kaufmann، نويسنده , , Dieter E.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
2685
To page
2688
Abstract
The C–C coupling of the two bicyclic, unsaturated dicarboximides 6 and 8 with aryl and hetaryl halides gave under reductive Heck conditions the 5-substituted N-phenylbicyclo[2.2.1]heptane-2,3-dicarboximides 7 and 9. Reduction of these imides opens a new access to the bridged perhydroisoindole derivatives 12 and 14 with prospective biological activity.
Keywords
PALLADIUM , C–C coupling , Aromatics , homogenous catalysis , Amine , Reduction
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1858975
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