tert-Butyldimethylsilyloxytrichloromethylmethane—readily accessible and robust protecting group for (hetero)aryl aldehydes

The tert-butyldimethylsilyloxytrichloromethylmethane (TBSTCM) substituent serves as a readily accessible masking group for aromatic and heteroaromatic aldehydes. The TBSTCM substituent is compatible with a range of common reagents and offers several strategic advantages over alternative aldehyde protecting groups.