Title of article
Novel 6-position modified 1-thioalkyl-lincosamines
Author/Authors
O’Dowd، نويسنده , , Hardwin and Lewis، نويسنده , , Jason G. and Gordeev، نويسنده , , Mikhail F.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
2979
To page
2981
Abstract
A general method for the synthesis of 6-position modified lincosamines via stereospecific nucleophilic addition to readily available galactose 6-nitrone has been developed. A new route for the stereospecific installation of thioalkyl groups at the 1-position was also developed. These methods allow access to a variety of new derivatives of antibacterial lincosamides.
Keywords
Lincosamides , Aminosugars , Diastereoselective addition , Thiogalactosides , Nitrones
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859107
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