Title of article
A new efficient synthesis of isothiocyanates from amines using di-tert-butyl dicarbonate
Author/Authors
Munch، نويسنده , , Henrik and Hansen، نويسنده , , Jon S. and Pittelkow، نويسنده , , Michael L. Christensen، نويسنده , , Jّrn B. and Boas، نويسنده , , Ulrik، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
3117
To page
3119
Abstract
Alkyl and aryl amines are converted smoothly to the corresponding isothiocyanates via the dithiocarbamates in good to excellent yields using di-tert-butyl dicarbonate (Boc2O) and 1–3 mol % of DMAP or DABCO as catalyst. As most of the byproducts are volatile, the work-up involves simple evaporation of the reaction mixture.
Keywords
Isothiocyanate , Thiourea , Amine , di-tert-butyl dicarbonate
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859175
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