Title of article
A one-pot synthesis of 2,3-dihydro-1H-pyrrolo[3,2-c]quinolines
Author/Authors
Tomaszewski، نويسنده , , Miroslaw J. and Whalley، نويسنده , , Adam and Hu، نويسنده , , Yun-Jin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
3172
To page
3175
Abstract
A one-pot synthesis of the 2,3-dihydro-1H-pyrrolo[3,2-c]quinoline core from substituted 2-iodoanilines and 2,3-dihydro-1H-pyrrole was achieved using 10 mol % Pd(PPh3)4, and K2CO3 in 1,4-dioxane at 170 °C for 1 h in a microwave oven. This reaction can be carried out on a gram scale. The proposed mechanism involves a Heck-coupling reaction followed by intra-molecular Schiff base formation and double bond migration.
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859200
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