Title of article :
Synthesis of 1,1-disubstituted tetrahydro-β-carbolines from 2-methyleneaziridines
Author/Authors :
Mumford، نويسنده , , Peter M. and Shiers، نويسنده , , Jason J. and Tarver، نويسنده , , Gary J. and Hayes، نويسنده , , Jerome F. and Shipman، نويسنده , , Michael، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
Ring opening of indole functionalised methyleneaziridines (3a–c, 7) with alcohols in the presence of boron trifluoride etherate leads to the formation of 1,1-disubstituted tetrahydro-β-carbolines in moderate to good yields (37–83%).
Keywords :
Ring opening , Nitrogen Heterocycles , strained compounds , Pictet–Spengler , Aziridines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
