Title of article :
Hydrogen bond catalyzed chemoselective N-tert-butoxycarbonylation of amines
Author/Authors :
Khaksar، نويسنده , , Samad and Heydari، نويسنده , , Akbar and Tajbakhsh، نويسنده , , Mahmood and Vahdat، نويسنده , , Seyed Mohammad، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
A novel, chemoselective mono-N-Boc protection of various structurally diverse amines with di-tert-butoxypyrocarbonate (Boc)2O is described that relies on selective carbonyl activation by hydrogen bond formation. This mild, acid- and metal-free process requires only catalytic amounts of thiourea as hydrogen bond donor.
Keywords :
Amines , (Boc)2O , Thiourea , Hydrogen bonding , Chemoselective
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
