Author/Authors :
Sato، نويسنده , , Kazuyuki and Yuki، نويسنده , , Takashi and Tarui، نويسنده , , Atsushi and Omote، نويسنده , , Masaaki and Kumadaki، نويسنده , , Itsumaro and Ando، نويسنده , , Akira، نويسنده ,
Abstract :
The treatment of silyl enol ethers of ketones with CF3–I and Et2Zn in the presence of RhCl(PPh3)3 in DME gave α-trifluoromethyl ketones in good yields. The reaction can be widely applicable to silyl enol ethers derived from aliphatic or aromatic ketones. In the absence of the rhodium catalyst, the reaction was very slow and the yields were quite poor.
Keywords :
Rhodium , ?-Position , Silyl enol ether , fluorine , Trifluoromethyl
