Title of article :
Chiral N-phosphonyl imine chemistry: asymmetric 1,2-additions of allylmagnesium bromides
Author/Authors :
Kattuboina، نويسنده , , Adiseshu and Kaur، نويسنده , , Parminder and Nguyen، نويسنده , , Thao and Li، نويسنده , , Guigen، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
Chiral N-phosphonyl homoallylic amines were synthesized by the reaction of allylmagnesium bromide with chiral N-phosphonyl imines. The C2-symmetric chiral N-phosphonyl group was optimized for this reaction. Excellent yields and good diastereoselectivities were obtained for eight examples.
Keywords :
Chiral N-phosphonyl imines , Grignard reagents , Homoallylic Amines , 2-addition , Allylmagnesium bromide , 1
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
