Author/Authors :
Liu، نويسنده , , Hai-Ling and Jiang، نويسنده , , Huanfeng and Zhang، نويسنده , , Min and Yao، نويسنده , , Wenjuan and Zhu، نويسنده , , Qiu-Hua and Tang، نويسنده , , Zhou، نويسنده ,
Abstract :
An efficient and general one-pot procedure for the synthesis of pyrazoles from acid chlorides, terminal alkynes and hydrazines was described via a coupling and cyclocondensation sequence. Acid chlorides coupled with terminal alkynes to give α,β-unsaturated ynones, and in situ converted into pyrazoles by the cycloaddition of hydrazines. The desired pyrazoles were obtained with 15–85% isolated yields.
