Title of article :
A facile Horner–Wadsworth–Emmons route to 2-quinolones
Author/Authors :
Peters، نويسنده , , Jens-Uwe and Capuano، نويسنده , , Tony and Weber، نويسنده , , Silja and Kritter، نويسنده , , Stéphane and Sنgesser، نويسنده , , Matthias، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
2-Quinolones are prepared from o-aminophenylketones by N-acylation with phosphonoalkanoylchlorides, followed by an intramolecular Horner–Wadsworth–Emmons olefination. The transformation proceeds under mild conditions, is generally applicable, gives good yields and can be performed either in two steps or as a one-pot reaction.
Keywords :
N-heterocycles , 2-Quinolones , Cyclisation , Olefination
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters