Title of article
A facile Horner–Wadsworth–Emmons route to 2-quinolones
Author/Authors
Peters، نويسنده , , Jens-Uwe and Capuano، نويسنده , , Tony and Weber، نويسنده , , Silja and Kritter، نويسنده , , Stéphane and Sنgesser، نويسنده , , Matthias، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
4029
To page
4032
Abstract
2-Quinolones are prepared from o-aminophenylketones by N-acylation with phosphonoalkanoylchlorides, followed by an intramolecular Horner–Wadsworth–Emmons olefination. The transformation proceeds under mild conditions, is generally applicable, gives good yields and can be performed either in two steps or as a one-pot reaction.
Keywords
N-heterocycles , 2-Quinolones , Cyclisation , Olefination
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859573
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