• Title of article

    The first total synthesis and structural determination of TMC-264

  • Author/Authors

    Tatsuta، نويسنده , , Kuniaki and Furuyama، نويسنده , , Akiho and Yano، نويسنده , , Tomoe and Suzuki، نويسنده , , Yasuaki and Ogura، نويسنده , , Takashi and Hosokawa، نويسنده , , Seijiro، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    4
  • From page
    4036
  • To page
    4039
  • Abstract
    The first total synthesis and structural determination of TMC-264 has been accomplished. Regioselective bromination, regioselective methoxymethylation, and nickel(0)-Lewis acid-mediated cyclization afforded multi-functionalized 1-methyl-dibenzo[b,d]-pyran skeleton.
  • Keywords
    total synthesis , absolute configuration , Antiallergic agent , Regioselective methoxymethylation , Biaryl coupling , TMC-264
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2008
  • Journal title
    Tetrahedron Letters
  • Record number

    1859576