Author/Authors :
van den Hoogenband، نويسنده , , Adri and Lange، نويسنده , , Jos H.M. and Terpstra، نويسنده , , Jan Willem and Koch، نويسنده , , Melle and Visser، نويسنده , , Gerben M. and Visser، نويسنده , , Martin and Korstanje، نويسنده , , Ties J. and Jastrzebski، نويسنده , , Johann T.B.H.، نويسنده ,
Abstract :
A Ruphos-mediated Suzuki cross-coupling between (hetero)aryl bromides and secondary alkyltrifluoroborates is described using palladium catalysis. The Ruphos ligand showed superior properties as compared to S-Phos in this type of reaction. This method constitutes a valuable extension to current methods for the straightforward production of secondary-alkylated (hetero)aryl derivatives.
