Title of article
Organocatalytic asymmetric nitrocyclopropanation of α,β-unsaturated aldehydes
Author/Authors
Vesely، نويسنده , , Jan and Zhao، نويسنده , , Gui-Ling and Bartoszewicz، نويسنده , , Agnieszka and Cَrdova، نويسنده , , Armando، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
4209
To page
4212
Abstract
A novel organocatalytic highly enantioselective nitrocyclopropanation reaction of α,β-unsaturated aldehydes is presented. The 1-nitro-2-formylcyclopropane derivatives synthesized from this catalytic transformation were converted to the corresponding β-nitromethyl-acid esters, which are excellent precursors of GABA analogues such as Baclofen, by subsequent organocatalytic chemoselective ring-opening.
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859666
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