Author/Authors :
Kommreddy، نويسنده , , Amitha and Bowsher، نويسنده , , Michael S. and Gunna، نويسنده , , Meena R. and Botha، نويسنده , , Kirankumar and Vinod، نويسنده , , Thottumkara K.، نويسنده ,
Abstract :
IBX derivative 6, synthesized in two steps from 2-aminoterephthalic acid, 8, is soluble in both DMF and water. A variety of alcohols are oxidized using 6 in DMF with ease and selectivity identical to that of parent IBX. However, oxidations carried out in water and other aqueous solvent mixtures using 6 exhibit unique selectivities toward different substrates and provide products different from reactions carried out in DMF. A mechanistic rationale is provided for this solvent dependent behavior of 6.
