Title of article :
First synthesis of 4,5-dihydro-3(2H)-pyridazinones via Zn-mediated hydrohydrazination
Author/Authors :
Alex، نويسنده , , Karolin and Tillack، نويسنده , , Annegret and Schwarz، نويسنده , , Nicolle and Beller، نويسنده , , Matthias، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
The hydrohydrazination of 4-pentynoic acid with different arylhydrazines proceeds smoothly in the presence of zinc chloride. The domino amination–amidation sequence leads to aryl-substituted 4,5-dihydro-3(2H)-pyridazinones.
Keywords :
Zinc , hydrazine , Hydroamination , Intermolecular , Pentynoic acid , Pyridazinone
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters