Author/Authors :
Matiychuk، نويسنده , , Vasyl S. and Lesyk، نويسنده , , Roman B. and Obushak، نويسنده , , Mykola D. and Gzella، نويسنده , , Andrzej and Atamanyuk، نويسنده , , Dmytro V. and Ostapiuk، نويسنده , , Yuri V. and Kryshchyshyn، نويسنده , , Anna P.، نويسنده ,
Abstract :
Various novel 3,5a,6,11b-tetrahydro-2H,5H-chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazol-2-ones were synthesized in 60–80% yields via domino-Knoevenagel–hetero-Diels–Alder reactions of 4-thioxo-1,3-thiazolidin-2-one with 3,7-dimethyl-6-octenal, 2-allyloxybenzaldehydes and 2-formylphenyl (E)-3-aryl-2-propenoates with base catalysis. The possibility of stereo- and regioselective cycloaddition was investigated.