Title of article :
FeCl3-catalyzed alkylation of indoles with 1,3-dicarbonyl compounds: an expedient synthesis of 3-substituted indoles
Author/Authors :
Yadav، نويسنده , , J.S. and Reddy، نويسنده , , B.V. Subba and Praneeth، نويسنده , , K.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
Indoles undergo smooth alkylation at the 3-position with 1,3-dicarbonyl compounds in the presence of 20 mol % of FeCl3 under mild reaction conditions to produce a wide range of 3-substituted indoles in excellent yields and with high E-selectivity.
Keywords :
indoles , 1 , 3-diketones , Iron(III) reagents , C-3 alkylation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
