Author/Authors :
Chen، نويسنده , , Xiang and Wu، نويسنده , , Jun and Shang، نويسنده , , Zhicai and Chen، نويسنده , , Meifeng and Sun، نويسنده , , Yanping and Lv، نويسنده , , Jing and Lei، نويسنده , , Meikang and Zhang، نويسنده , , Peizhi، نويسنده ,
Abstract :
LiAlH4 and NaBH4 were found to mediate the conversion of 2-(pyrimidyl-2-ylsulfanyl)-N-arylbenzamides and 2-(triazinyl-2-ylsulfanyl)-N-arylbenzamides into pyrimidyl and triazinyl amines under notably mild conditions via a novel reductive rearrangement mechanism. These reactions invent a new route to prepare amines, which are a kind of important biologically active compounds and provide the first insight into a novel hydride-promoted reductive rearrangement of amides.
