• Title of article

    An efficient approach to the stereoselective synthesis of 2,6-disubstituted dihydropyrans via stannyl-Prins cyclization

  • Author/Authors

    Dziedzic، نويسنده , , Magdalena and Furman، نويسنده , , Bart?omiej، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    4
  • From page
    678
  • To page
    681
  • Abstract
    A general method has been developed for the stereoselective construction of 2,6-disubstituted dihydropyrans based on the Lewis acid-catalyzed intramolecular reactions of oxocarbenium ions with vinylstannanes. This novel methodology was applied to the enantioselective total synthesis of (−)-centrolobine.
  • Keywords
    (?)-Centrolobine , Dihydropyrans , Prins cyclization , Vinylstannanes
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2008
  • Journal title
    Tetrahedron Letters
  • Record number

    1860137