• Title of article

    An efficient chiral synthesis of fluoro-containing amino acids: N-benzyloxycarbonyl-2-amino-4,4-difluorobutyric acid methyl ester and its analogs

  • Author/Authors

    Hu، نويسنده , , Zilun and Han، نويسنده , , Wei، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    2
  • From page
    901
  • To page
    902
  • Abstract
    Fluoro-containing amino acids, N-benzyloxycarbonyl-2-amino-4,4-difluorobutyric acid methyl ester and analogs, were prepared in high enantiomeric excess. Incorporation of 2-amino-4,4-difluoro butyric acid as P1 group provided a potent HCV NS3 protease inhibitor.
  • Keywords
    2-Amino-4 , 4-difluorobutyric acid , Fluoro amino acid , HCV protease inhibitor
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2008
  • Journal title
    Tetrahedron Letters
  • Record number

    1860237

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1860237