Author/Authors :
Pierre Haquette، نويسنده , , Pierre and Talbi، نويسنده , , Barisa and Canaguier، نويسنده , , Sigolène and Dagorne، نويسنده , , Samuel and Fosse، نويسنده , , Céline and Martel، نويسنده , , Annie and Jaouen، نويسنده , , Gérard and Salmain، نويسنده , , Michèle، نويسنده ,
Abstract :
The cationic (η6-arene)ruthenium complexes 6–9 containing a chloroacetamide or a maleimide functional group on the arene ligand were synthesized and successfully used to introduce ruthenium(II) species to the active site of the cysteine endoproteinase papain in a site-directed and covalent fashion as shown by enzymatic and ESI-MS studies.