Title of article
Functionalized cationic (η6-arene)ruthenium(II) complexes for site-specific and covalent anchoring to papain from papaya latex. Synthesis, X-ray structures and reactivity studies
Author/Authors
Pierre Haquette، نويسنده , , Pierre and Talbi، نويسنده , , Barisa and Canaguier، نويسنده , , Sigolène and Dagorne، نويسنده , , Samuel and Fosse، نويسنده , , Céline and Martel، نويسنده , , Annie and Jaouen، نويسنده , , Gérard and Salmain، نويسنده , , Michèle، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
4670
To page
4673
Abstract
The cationic (η6-arene)ruthenium complexes 6–9 containing a chloroacetamide or a maleimide functional group on the arene ligand were synthesized and successfully used to introduce ruthenium(II) species to the active site of the cysteine endoproteinase papain in a site-directed and covalent fashion as shown by enzymatic and ESI-MS studies.
Keywords
Ruthenium complexes , Papain , S-Alkylation
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860403
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