Title of article
Aminomethylation of chiral silyl enol ethers: access to β2-homotryptophane and β2-homolysine derivatives
Author/Authors
Moumné، نويسنده , , Roba and Larregola، نويسنده , , Maud and Boutadla، نويسنده , , Youcef and Lavielle، نويسنده , , Solange and Karoyan، نويسنده , , Philippe، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
4704
To page
4707
Abstract
We describe here the aminomethylation of chiral silyl enol ether derivatives using iminium ion. The choice of judicious precursors with adequate protecting groups for the silylation/aminomethylation step was required to achieve the synthesis of β2-homotryptophane in few steps. The same methodology was used to prepare a β2-homolysine derivative.
Keywords
?2-Amino acids , Aminomethylation , Chiral silyl enol ether derivatives , iminium ion
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860427
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