Author/Authors :
Zلrraga، نويسنده , , Miguel and Zلrraga، نويسنده , , Ana Marيa and Rodrيguez-Berrocal، نويسنده , , Benito and Pérez، نويسنده , , Claudia and Paz، نويسنده , , Cristian and Paz، نويسنده , , Pablo and Sanhueza، نويسنده , , Carlos، نويسنده ,
Abstract :
Drimane sesquiterpenes are highly valuable due to their strong biological activity. In this work, we report the enhanced antifungal activity of 11-guanidinodrimene, a new compound derived from drimenol. The binding of the guanidine group at the C-11 carbon increased the antifungal activity when tested against Candida albicans, one of the most commonly found human pathogens.