Title of article :
Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement
Author/Authors :
Lauria، نويسنده , , Antonino and Abbate، نويسنده , , Ilenia and Patella، نويسنده , , Chiara and Gambino، نويسنده , , Noemi and Silvestri، نويسنده , , Arturo and Barone، نويسنده , , Giampaolo and Almerico، نويسنده , , Anna Maria، نويسنده ,
Abstract :
Derivatives of the new ring system pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine were synthesized from the corresponding angular isomers, through a Dimroth rearrangement, in quantitative yields. Preliminary computational studies demonstrated that this class of compounds could be a good candidate as DNA intercalating agents.
