Title of article
Highly regioselective palladium-catalyzed methoxycarbonylation of styrene using chiral ferrocene- and biphosphole-based ligands
Author/Authors
Diab، نويسنده , , Lisa and Gouygou، نويسنده , , Maryse and Manoury، نويسنده , , Eric and Kalck، نويسنده , , Philippe and Urrutigoïty، نويسنده , , Martine، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
5186
To page
5189
Abstract
The methoxycarbonylation of styrene has been studied using Pd(OAc)2/L/acid catalytic systems with L being chiral ferrocene- and biphosphole-based ligands. Good activities are obtained in mild conditions. Chemoselectivities and regioselectivities (up to 98% in favour of the branched isomer) are excellent but enantioselectivities remain moderate (ee up to 17%).
Keywords
Methoxycarbonylation , P , S ligands , P , P Ligands , Enantioselectivity , Vinylarenes , regioselectivity , PALLADIUM
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860710
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