Author/Authors :
Serieys، نويسنده , , Audrey and Botuha، نويسنده , , Candice and Chemla، نويسنده , , Fabrice and Ferreira، نويسنده , , Franck and Pérez-Luna، نويسنده , , Alejandro، نويسنده ,
Abstract :
The high yielding synthesis of symmetrical carboxylic anhydrides from acid chlorides mediated by zinc dust in the presence of dimethylformamide is presented. A mechanism involving the reductive insertion of zinc(0) into the C–Cl bond of a Vilsmeier-type iminium intermediate as the crucial step is also proposed.
Keywords :
Zinc , Vilsmeier iminiums , Carboxylic anhydrides , Reductive insertion , carbenoids
