Title of article
Synthesis and characterization of 2-substituted bornane pharmacophores for novel cannabinergic ligands
Author/Authors
Richard I. Duclos Jr.، نويسنده , , Richard I. and Lu، نويسنده , , Dai and Guo، نويسنده , , Jianxin and Makriyannis، نويسنده , , Alexandros، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
5587
To page
5589
Abstract
Analogously to the fenchyl and adamantyl groups, the bornyl and epimeric isobornyl groups are compact lipophilic substituents that can be incorporated into drug design to improve pharmacological or physicochemical properties. Methods are reported for the synthesis and characterization of 2-substituted norbornanes and bornanes that can serve as novel cannabinergic ligand intermediates.
Keywords
Bornyl , NMR , Chiral HPLC , Isobornyl , Norbornane
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860880
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