Title of article
Microwave-assisted, Mo(CO)6-mediated, palladium-catalyzed amino-carbonylation of aryl halides using allylamine: from exploration to scale-up
Author/Authors
Appukkuttan، Prasad نويسنده , , Prasad and Axelsson، نويسنده , , Linda and der Eycken، نويسنده , , Erik Van and Larhed، نويسنده , , Mats، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
5625
To page
5628
Abstract
Palladium-catalyzed aminocarbonylations of various (hetero)aryl halides with allylamine using Mo(CO)6 as a solid, in situ CO source, were explored. Microwave-enhanced conditions proved to be highly useful in promoting the conversions in a mere 10–20 min with various (hetero)aryl iodides, bromides and chlorides. The scale-up of a microwave-enhanced aminocarbonylation to 25 mmol scale was performed successfully.
Keywords
microwave , Scale-up , Aryl chloride , PALLADIUM , carbonylation
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860904
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