Title of article
C- and N-cyanoacetylation of 6-aminopyrimidines with cyanoacetic acid and acetic anhydride
Author/Authors
Quiroga، نويسنده , , Jairo and Trilleras، نويسنده , , Jorge and Gلlvez، نويسنده , , Jaime and Insuasty، نويسنده , , Braulio and Abonيa، نويسنده , , Rodrigo and Nogueras، نويسنده , , Manuel and Cobo، نويسنده , , Justo and Marchal، نويسنده , , Antonio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
5672
To page
5675
Abstract
A series of 6-aminopyrimidines are cyanoacetylated with a mixture of cyanoacetic acid and acetic anhydride. When pyrimidin-4(3H)-ones are used as substrates, the substitution occurs at C-5, however, when the substrates are substituted pyrimidines at the C-2 and C-4, the cyanoacetylation takes place at the exocyclic amino group.
Keywords
Cyanoacetylation , 6-Aminopyrimidines , 3-Pyrimidinyl-3-oxopropanenitriles
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860935
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