Title of article :
Synthesis of homoallylic oxygenated α-methylene-γ-butyrolactones: a model for preparing biologically active natural lactones
Author/Authors :
Sass، نويسنده , , Daiane Cristina and Oliveira، نويسنده , , Kleber Thiago de and Constantino، نويسنده , , Mauricio Gomes، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
In this Letter we describe a 12% overall yield synthesis of a model for homoallylic oxygenated α-methylene-γ-butyrolactones with relative stereochemistry defined by selective hydrogenation with Rh/Al2O3. The synthesis was realized in 9 steps involving simple reactions.
Keywords :
?-Methylene-?-butyrolactones , Synthesis , natural products
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters