Title of article :
Samarium diiodide-promoted electrophilic amination of ketone enolates: efficient synthesis of quaternary carbon-containing α-aminated ketones
Author/Authors :
Sun، نويسنده , , Xing-Wen and Wang، نويسنده , , Wei and Xu، نويسنده , , Ming-Hua and Lin، نويسنده , , Guo-Qiang، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Pages :
3
From page :
5807
To page :
5809
Abstract :
An efficient and practical electrophilic amination method that allows the preparation of useful quaternary carbon-containing α-aminoketones was developed. The reaction proceeds regiospecifically via a samarium enolate intermediate at room temperature in the presence of mild reducing agent SmI2. Unlike the most reported lithium enolate cases, this new amination method does not require the use of strong base such as BuLi or LDA.
Journal title :
Tetrahedron Letters
Serial Year :
2008
Journal title :
Tetrahedron Letters
Record number :
1861027
Link To Document :
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