An efficient synthesis of 2,3-diaryl (3H)-quinazolin-4-ones via imidoyl chlorides

A practical and efficient three step synthetic route to 2,3-diaryl (3H)-quinazolin-4-ones has been developed. The key step involves microwave-assisted condensation of an imidoyl chloride with an aryl amine. This methodology affords the products cleanly and in high yields.