Title of article :
A new route to eremophilanes: synthesis of (±)-eremophilenolide, (±)-eremophiledinone, and (±)-deoxyeremopetasidione
Author/Authors :
Srinivas، نويسنده , , P. and Srinivasa Reddy، نويسنده , , D. and Shiva Kumar، نويسنده , , K. and Dubey، نويسنده , , P.K. and Iqbal، نويسنده , , Javed and Das، نويسنده , , Parthasarathi، نويسنده ,
Abstract :
A new and efficient route to the family of eremophilanes is reported. Key steps are the highly stereocontrolled Diels–Alder reaction and aldol condensation to furnish a cis-decalin system with the desired stereochemistry present in the eremophilane family of natural products. This approach is general and was utilized for the synthesis of (±)-eremophilenolide, (±)-eremophiledinone, and (±)-deoxyeremopetasidione.
