Title of article
Organocatalytic synthesis of α-hydroxy and α-aminophosphonates
Author/Authors
Vahdat، نويسنده , , Seyed Mohammad and Baharfar، نويسنده , , Robabeh and Tajbakhsh، نويسنده , , Mahmood and Heydari، نويسنده , , Akbar and Baghbanian، نويسنده , , Seyed Meysam and Khaksar، نويسنده , , Samad، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
6501
To page
6504
Abstract
A new and highly flexible procedure is described for the synthesis of α-amino- and α-hydroxy phosphonates. In the presence of a catalytic amount of oxalic acid (10 mol %), trimethyl phosphite reacts with aldehydes or imines (generated in situ from an aldehyde and an amine) to yield the corresponding coupled products in good yield.
Keywords
solvent-free , ?-Hydroxy phosphonate , organocatalyst , ?-Aminophosphonates
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861485
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