Author/Authors :
Vahdat، نويسنده , , Seyed Mohammad and Baharfar، نويسنده , , Robabeh and Tajbakhsh، نويسنده , , Mahmood and Heydari، نويسنده , , Akbar and Baghbanian، نويسنده , , Seyed Meysam and Khaksar، نويسنده , , Samad، نويسنده ,
Abstract :
A new and highly flexible procedure is described for the synthesis of α-amino- and α-hydroxy phosphonates. In the presence of a catalytic amount of oxalic acid (10 mol %), trimethyl phosphite reacts with aldehydes or imines (generated in situ from an aldehyde and an amine) to yield the corresponding coupled products in good yield.
Keywords :
solvent-free , ?-Hydroxy phosphonate , organocatalyst , ?-Aminophosphonates
